Magtein® This is the most thoroughly researched magnesium supplement for supporting brain function, memory, sleep, and possibly concentration in ADHD. It is the only magnesium compound (Mg-L-threonate) that can cross the blood-brain barrier and thus act directly in the brain.

The clinical data are based on high-quality human studies (double-blind, randomized). Dosages can be panoramically determined from 1–2 g/day rated as effective and well tolerated:

🧠 1. Improved cognitive functions in healthy adults

• study: Double-blind, placebo-controlled, n = 109 healthy adults (18–65 years)
   
• formulation: Magtein® – Magnesium L-threonate combined with phosphatidylserine and vitamin C & D (you can also get everything in our shop)
   
• dosage: 2 g/day
   
• Length of time: 30 days
   
• Result: Significant improvement in all five subtests of a clinical memory test as well as in the overall memory quotient compared to the placebo group. https://aidp.com/2022/12/21/aidp-inc-announces-a-new-magtein-human-clinical-published-study-in-nutrients/ 
   

🌙 2. Sleep quality & Daily function

• study: Randomized, double-blind, placebo-controlled
   
• Participant: 80 adults (35–55 years) with self-reported sleep problems
   
• dosage: 1 g/day Magnesium L-Threonate
   
• Length of time: 3 weeks
   
• Result:
   
  • Improved depth & REM sleep phases (measured via Oura ring)
     
  • Improved subjective values ​​(Insomnia Severity Index, daily energy, mood) https://www.nutraceuticalsworld.com/breaking-news/magnesium-l-threonate-improves-sleep-quality-clinical-study/ 
     

💤 3. Support for ADHD symptoms (piloted)

• Study design: Open pilot study (no control group)
   
• Participant: 15 adults with ADHD
   
• dosage: 2 g/day 
   
• Length of time: up to 12 weeks
   
• Result: Approximately 50% showed improved concentration and reduced ADHD symptoms. 
   

🧪 4.dosage & Bioavailability

• Effective elemental magnesium dose For cognitive effects: 108–144 mg/day – below the RDA (350–420 mg/day) https://europepmc.org/article/PMC/9786204?utm 
   
• Special feature: Magnesium L-threonate increases magnesium levels in the brain and cerebrospinal fluid significantly more than other magnesium compounds. https://pmc.ncbi.nlm.nih.gov/articles/PMC9786204/?utm 
   

⚠️ Instructions for use

• Very good tolerability at dosages <=2 g/day
   
• Effect: Usually visible after 3–4 weeks of regular use.
   
• Interactions: No known relevant drug interactions