Collagen comes i.d.R. of animal origin. Our Ovoderm® collagen has a Purely vegetarian collagen profile from eggshell membranes From the quality manufacturer EGGNOVO in Spain. This membrane lines the inside of the eggshell and is particularly rich in structural proteins and other ingredients that give the membrane its characteristic strength and elasticity. The patented extraction process ensures a Exceptionally high content of over 90% total protein achieved.

The original branded raw material Ovoderm® provides a Collagen complex in its natural form, consisting of 25% elastin, 22% collagen types I, V and X, and 3% hyaluronic acid and 2% other glycosaminoglycans. This is a crucial advantage over many other (animal-based) collagen products on the market, as it significantly reduces the required dosage.

The only other ingredient we add is the pleasantly scented essential lemon peel oil powder, which has been specially developed for internal use.

Collagen, elastin and hyaluronic acid

Collagen Collagen, comprising over 30% of the total protein weight, is the most abundant protein in the human body and exists in different types depending on the tissue. As a structural protein, it provides elasticity and strength to cartilage, tendons, ligaments, connective tissue, skeletal muscles, blood vessels, skin, bones, and teeth. Collagen synthesis involves the linking of amino acids, along with several essential vitamins, minerals, and trace elements, to form a polypeptide chain. Thicker collagen fibers are then formed through aggregation and cross-linking.

· Type I collagen: 90% of the collagen in the human body, especially in skin, bones, tendons and cartilage.

· Collagen type V: in cell junctions of the epidermis and dermis

· Collagen type X: in cartilage chondrocytes

Elastin Like collagen, elastin is a structural protein. Unlike collagen, which primarily provides strength, elastin is stretchable and elastic.

Hyaluronic acid is u.aHyaluronic acid is involved in wound healing and is an important component of synovial fluid ("joint lubricant"), which forms a protective lubricating film on the cartilage in the joint. It is also responsible for supplying the cartilage with nutrients and acts as a kind of "shock absorber"; this property is due to hyaluronic acid's ability to bind large amounts of water. This ability is also the reason why hyaluronic acid is so popular in cosmetics.

Mechanisms of action

1. Promotion of collagen synthesis
   In vitro and in animal models, it was shown that oral administration of eggshell membrane the Expression of COL1A1 and COL3A1 significantly increased in the skin, thus supporting the formation of new collagen fibers.
2. Inhibition of matrix-degrading enzymes
   The activity of MMP-1 and MMP-2, which are responsible for the breakdown of collagen, is reduced after ESM administration – an effect that leads to less wrinkling.
3. Anti-inflammatory and antioxidant effects
   In UVB-exposed models, ESM lowers the mRNA expression of pro-inflammatory cytokines (IL-1, IL-6, TNF-α) and increases the activity of antioxidant enzymes such as SOD1.
   
   (Source: https://link.springer.com/article/10.1007/s13273-022-00291-5?utm)

Clinical trials

study	design && Dose	Main result
Aguirre et al. 2018	Randomized, double-blind, placebo-controlled trial; 300 mg Ovoderm®/day for 60 days (n=16)	– Transepidermal water loss (TEWL) ↓ 43% – Skin elasticity ↑ 13 % (p&<0.05)
Park et al. 2025 (in press)	Randomized, double-blind, placebo-controlled trial; 600 mg ESM (Ovoderm®-AS)/day for 12 weeks in women (25–60 years old)	Significant improvements in Skin elasticity, Wrinkle reduction and Moisture profile
BiovaBio™ (PMC7418556, 2019)	Randomized, double-blind, placebo-controlled trial; 450 mg hydrolyzed ESM/day for 12 weeks (n=88)	– Wrinkle depth (Crow's Feet) ↓ in 4 weeks – Skin condition and Hair thickness ↑ significant (p&<0.05)
Ovolux™ (Ovolux™ vs. Placebo, 2020)	Randomized; 300 mg unhydrolyzed ESM/day for 12 weeks (n=63)	– Skin elasticity ↑ (Cutometer®) – Positive trends for hair and nail health

Dosage and safety

• Recommended daily dose: 300 mg (1 capsule)
• Dosage form: vegan capsule, on an empty stomach or with a meal
• SecuritySeveral studies report no unwanted effects at the tested dosages; laboratory analyses confirm purity and microbiological safety.

Conclusion

Ovoderm® collagen from eggshell membrane is a high-quality, vegetarian nutricosmetic, which through clinically proven Mechanisms that slow down skin aging processes and the skin barrier can strengthen. The combination of Collagen, GAGs and antioxidant effects This makes Ovoderm® the best option for health-conscious consumers seeking a sustainable and vegetarian alternative to conventional collagen.