Nattokinase 2800 FU/capsule

Natto is a Japanese dish made from fermented soybeans, which in Japan is both a completely normal dish and is recommended in Japanese naturopathy as a traditional remedy for cardiovascular diseases.

In Japan, natto is also called "vegetable cheese" and is often eaten for breakfast with vegetables and rice. In contrast, natto has not yet gained popularity in European diets, likely due to its very acquired taste, strong smell, and unappetizing appearance.

Nattokinase is one of several enzymes in natto and is obtained from the fermentation of soybeans. For this process, the soybeans are cooked and then fermented using the bacterium Bacillus subtilis. During this process, the bacteria produce the enzyme nattokinase, which consists of 275 amino acids, enabling the metabolism of the soy protein.

The name NattoKINASE resulted from the mistaken belief that nattokinase belonged to the kinase enzyme group. Later, however, it was discovered that it actually belongs to the group of proteases, which break down proteins.

As already explained, nattokinase is an enzyme from the protease enzyme group – just like the two endogenous enzymes plasmin and thrombin, which are involved in blood clotting:

Thrombin promotes blood clotting by synthesizing fibrin, the "glue" that unfortunately can not only close wounds but also form blood clots. Plasmin, in turn, dissolves fibrin; this process is called "fibrinolysis". Several studies suggest that nattokinase – similar to plasmin – is activated via fibrinolytic, d.h. It may possess clot-dissolving properties. However, this explicitly does not constitute a claim regarding the efficacy of our product.

Why do you use a different method than with papain? & Bromelain capsules are not gastro-resistant?

Nattokinase, unlike the enzymes papain and bromelain, is significantly more acid-resistant and can therefore withstand stomach acid. Nattokinase is also more heat-resistant than many other enzymes and can survive temperatures up to 50 degrees Celsius.

Selected studies that support these statements:

“Characterization and fibrinolytic activity of Nattokinase” (1995, Nakamura et al.): This study investigated the fibrinolytic activity of nattokinase. It showed that the enzyme retains stable activity even when exposed to acidic conditions in the stomach.

“Effect of Nattokinase Supplementation on Blood Pressure and Fibrinolytic Activity in Healthy Subjects” (2009, Sumi et al.): This study investigates the effects of nattokinase on blood pressure and fibrinolysis. It showed u.a. also that the enzyme is effective even without a special enteric coating.

Who should NOT take nattokinase?

Nattokinase should not be taken with blood thinners, by those with a bleeding tendency, those with soy intolerance, before surgery, or by pregnant or breastfeeding women. Please discuss its use with your doctor.