Everyone knows it. There are days when you hardly have any appetite and then there are days when you could eat non-stop, even though you know perfectly well that you have actually eaten enough.
A whole range of hormones and hormone-like peptides are responsible for our feelings of hunger and satiety. The big players are insulin and leptin, but we can influence others too.
For example:
Glucagon-like peptide 1 (GLP-1)
GLP-1 is a peptide produced in the lower digestive tract and brain that causes the stomach to empty more slowly and leads to a longer feeling of fullness.
Various human studies have shown an opposite effect to ghrelin. Fatty and energy-rich food suddenly appears much less attractive under the influence of GLP-1.
GLP-1 is now available in various preparations as a medication and actually leads to an average weight loss of 4.5 kg in cases of severe obesity. The problem, however, is that this effect is not sustainable, as it has no effect on the existing insulin resistance and GLP-1 actually stimulates the pancreas to secrete even more insulin, which is why the medication is also used for diabetes.
If you stop taking it, the pounds will come back and the weight loss will not be big enough to achieve a real improvement in health. Some plant substances, such as substances from bitter orange, stimulate the release of GLP-1 and can therefore be helpful in not feeling hungry on an energy-reduced diet and in developing less of an appetite for counterproductive foods.
Substances that bind to the GLP-1 receptor in the body, such as bitter orange, can also be helpful. IN-SHAPE by QIDOSHA Bitter orange is cleverly combined with other stabilizing substances. It can be a helpful supplement both during a phase of reduced energy and especially afterwards.
Our author:
Dr. Simone Koch
Addition
The L-carnitine is a carrier for the fats from food (after beta-oxidation) into the mitochondria and the also contained coenzyme Q10 is important as part of the respiratory chain in the mitochondria. As a result, ATP formation (cellular energy) can be strengthened.