origin
Quercetin is a secondary plant compound (phytochemical). Secondary plant compounds exist in a wide variety of chemical structures, each with specific properties. Among the best-known groups of secondary plant compounds are polyphenols, isoflavones, and carotenoids. Quercetin belongs to the polyphenol group and specifically to the (bio)flavonoid subgroup. There are over 5,000 different types of bioflavonoids that occur naturally in plants. In plants, they are responsible for flower and leaf color, as well as for protection against UV radiation, herbivores, viruses, fungi, and bacteria. Quercetin is the most abundant flavonoid and serves as a precursor to other flavonoids.
Quercetin is absorbed into the body via the (v.aQuercetin is absorbed into the bloodstream from the small intestine. According to current studies, slightly less than half of the consumed amount is absorbed by the body, and it takes up to nine hours after ingestion for the quercetin to become available to the body. The body does not store quercetin permanently but excretes it again after approximately 35 hours. Therefore, quercetin should be administered regularly as part of a treatment regimen.
Happen
High levels of quercetin can be found, for example, in capers (approximately 1600 mg quercetin per kg), onions (approximately 284-486 mg quercetin per kg), chives (245 mg), cranberries (156 mg), blackcurrants (69 mg) and kale (60 mg).
Quercetin is involved v.a. in the outer shells or layers of plants Quercetin is found in various plants (e.g., tree bark) and fruits (e.g., grapes, apples, onions) to protect them from free radicals. This also means that virtually no quercetin is absorbed if the outer skins are removed before consumption. For example, quince peels can contain up to 180 mg of quercetin per kg. The fruit itself, however, contains hardly any significant amounts of quercetin, and only minimal amounts are found in its interior. Similarly, in onions, approximately 20% of the quercetin is located directly under the skin and is therefore usually removed during peeling.
Even the Cultivation method is relevant for the quercetin contentFor example, organically grown tomatoes contain approximately 80% more quercetin than those from conventional agriculture. Furthermore, heat during cooking can lead to further quercetin losses (studies indicate up to 25%).
Beneath the tree bark, it stings v.a. those of the oak tree with regard to the quercetin content, from which the name “quercetin” also results - because “quercusQuercetin is the Latin name for "oak"; more precisely, for the dyer's oak (Quercus velutina). However, very high quercetin content has also been found in the bark of other tree species over time. QIDOSHA quercetin is extracted from the Japanese pagoda tree (Sophora japonica), as its flower extract contains a particularly high amount of natural quercetin.
Benefits and mode of action
Since it has been There are hardly any scientific studies on quercetin in humans. There are so-called “Health Claims”, d.hHealth claims associated with taking this product are inadmissible. The available studies therefore refer to... v.a...based on laboratory and animal testing. However, since there are numerous promising starting points here, clinical trials in humans are to be expected in the near future.
It is undisputed that quercetin is a particularly important substance. powerful antioxidant Quercetin appears to be roughly comparable to OPC or epigallocatechin gallate (EGCG) from green tea leaves. The reason for this lies in the chemical structure of quercetin – it is a polyphenol that, instead of a sugar molecule, has an additional hydroxyl group.And the more OH groups a polyphenol has, the higher its antioxidant effect.
Another Special characteristics of flavonoids Quercetin's ability lies in its capacity to regenerate already oxidized substances (e.g., vitamins C and E). d.h. them their to restore antioxidant power.
In one Meta-study from 2019 Effects of quercetin in diabetes Based on animal studies, researchers were able to find that when doses of 10, 25 and 50 mg of quercetin per kg of body weight resulted in a significant difference in the mean serum glucose levels. https://pubmed.ncbi.nlm.nih.gov/30735748/
One Japanese study suggests that quercetin have an anti-allergic effect It could do this by inhibiting the so-called histamine H1 receptor (H1R). The severity of allergy symptoms increases proportionally to the activity of this receptor. https://pubmed.ncbi.nlm.nih.gov/23333628/
One Study by the University of Naples postulates a anti-inflammatory effect Quercetin, in principle, is able to lower concentrations of the tissue hormone prostaglandin E2 and the fatty acid derivative leukotriene B4. Both substances are relevant for initiating inflammatory processes and are significantly involved in the release of inflammatory mediators such as histamine. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.2042-7158.1988.tb05250.x
One Study from 2007: blood pressure lowering effect The study participants were given 730 mg of quercetin daily for almost a month, and a reduction in systolic (−7 ± 2 mmHg) and diastolic (−5 ± 2 mmHg) blood pressure was observed in patients with hypertension. Further clinical studies are therefore recommended. https://pubmed.ncbi.nlm.nih.gov/17951477/
How can I recognize a high-quality product?
When buying, you should ensure that the product is 100% natural. The premium flower extract should come from the Japanese pagoda tree (Sophora japonica) and ideally have an extract ratio of 15:1. The water-alcohol extract used in production should be highly purified and contain no chemical solvents. Capsules are perfect for integrating into your daily routine as a dietary supplement.
Legal consumer information
German and European law aims to protect consumers from potentially misleading claims about product effects. The statements made here refer to original Ayurvedic and Traditional Chinese Medicine (TCM) texts. This millennia-old, traditional knowledge is based on experiences passed down from generation to generation. It is not intended that the products described here have any effect in the sense of Western medicine. All products are dietary supplements; they are not medications and have no medicinal effect. If you are ill and require medical attention, please consult your doctor or pharmacist.
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